Anti-Hu CD14 Biotin

EXBIO

Anti-Hu CD14 Biotin

7

Flow cytometry: recommended dilution: 2-4 microg/ml.

Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

MEM-18

1 mg/ml

Biotin

IgG1

CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where it serves as a multifunctional lipopolysaccharide receptor. It is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.

Human, Primate

2°C to 8°C

12352203