Bio-Connect

Anti-Hu CD140a APC

1A-589
EXBIO
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
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Overview

  • Supplier
    EXBIO
  • Product Name
    Anti-Hu CD140a APC
  • Delivery Days Customer
    7
  • Application Supplier Note
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clone ID
    16A1
  • Conjugate
    APC (Allophycocyanin)
  • Isotype
    IgG1
  • Scientific Description
    CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b / PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration, the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects. CD140a has early developmental functions, mediates mesodermal cell migration, and later acts in signaling associated in epithelial-mesenchymal interactions.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203