Anti-Hu CD150 Purified Azide Free

EXBIO

Anti-Hu CD150 Purified Azide Free

7

Flow cytometry: Recommended dilution: 1-5 microg/ml.

Flow Cytometry, ImmunoPrecipitation, ImmunoCytoChemistry

Research Use Only

SLAM.4

1 mg/ml

IgG1

CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.

2°C to 8°C

12352203