Anti-Hu CD177 Purified

EXBIO

Anti-Hu CD177 Purified

7

Flow cytometry: Recommended dilution: 1 microg/ml. Western blotting: Non-reducing conditions.

Flow Cytometry, ImmunoPrecipitation, Western Blot

Research Use Only

MEM-166

1 mg/ml

IgG1

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

Human, Primate

2°C to 8°C

12352203