Anti-Hu CD205 Purified

EXBIO

Anti-Hu CD205 Purified

7

Western blotting: Only non-denatured samples. Flow cytometry: Recommended dilution: 1-4 microg/ml

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

HD30

1 mg/ml

IgG1

CD205, also known as DEC-205, is an endocytic receptor of macrophage mannose receptor family. This 205 kDa C-type lectin transmembrane protein mediates adsorptive uptake and its intracellular domain contains coated pit localization sequence and distal acidic motif, which is required for recycling beyond early endosomes through deeper MHC II+ late endosomes and lysosomes. This unique pathway of receptor-mediated uptake proves to be necessary for presentation of antigenic peptides at low doses of ligand. CD205 is responsible for uptake and processing of captured antigens for dendritic cells.

Human

2°C to 8°C

12352203