Anti-Hu CD23 APC
1A-689
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
Overview
- SupplierEXBIO
- Product NameAnti-Hu CD23 APC
- Delivery Days Customer7
- Application Supplier NoteFlow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- Clone IDEBVCS-5
- ConjugateAPC (Allophycocyanin)
- IsotypeIgG1
- Scientific DescriptionCD23 (Fc epsilon RII), the low affinity IgE receptor, is a 45 kDa type II membrane glycoprotein expressed more or less on eosinophils, follicular dendritic cells, Langerhans cells, mature B cells (mainly upon activation), EBV-transformed lymphoblasts, monocytes, and subpopulation of platelets. A soluble form of 37 kDa and other its fragments were also described. CD23 mediates IgE-dependent cytotoxicity by eosinophils and macrophages, and downregulates IgE secretion in response to high levels of IgE, involving release of pro-inflammatory cytokines.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203