Anti-Hu CD261 APC

EXBIO

Anti-Hu CD261 APC

7

Flow cytometry: Recommended dilution: 2-4 microg/ml.

Flow Cytometry

Research Use Only

DR-4-02

0.1 mg/ml

APC (Allophycocyanin)

IgG1

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).

Human

2°C to 8°C

12352203