Anti-Hu CD263 Purified Azide Free
10-518
ApplicationsFlow Cytometry
Product group Antibodies
Overview
- SupplierEXBIO
- Product NameAnti-Hu CD263 Purified Azide Free
- Delivery Days Customer7
- Application Supplier NoteFlow cytometry: Recommended dilution: 1-4 microg/ml.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- Clone IDTRAIL-R3-02
- Concentration1 mg/ml
- IsotypeIgG1
- Scientific DescriptionTRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).
- Storage Instruction2°C to 8°C
- UNSPSC12352203