Anti-Hu CD300a Purified

EXBIO

Anti-Hu CD300a Purified

7

Flow cytometry: Recommended dilution: 2 microg/ml. Western blotting: Positive material: HPB cell line, negative material: JURKAT human cell line, RAJI human cell line; non-reducing conditions.

Flow Cytometry, Western Blot

Research Use Only

MEM-260

1 mg/ml

IgG1

CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.

Human

2°C to 8°C

12352203