Anti-Hu CD34 Purified Azide Free

EXBIO

Anti-Hu CD34 Purified Azide Free

7

Functional application: The antibody QBEnd-10 induces homotypic adhesion of leukemic cell line. Flow cytometry: Recommended dilution: 5 microg/ml. Immunohistochemistry (paraffin sections): Recommended dilution: 2-8 microg/ml. Western blotting: Recommended dilution: 1-2 microg/ml, positive control: TF-1 cells.

Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

QBEnd-10

1 mg/ml

IgG1

CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

2°C to 8°C

12352203