Anti-Hu CD34 Purified

EXBIO

Anti-Hu CD34 Purified

7

Western blotting: Recommended dilution: 1-2 microg/ml; positive control: Kg-1a, TF-1 cells, non-reducing conditions. Flow cytometry: Recommended dilution: 2 microg/ml. Immunohistochemistry (paraffin sections): Recommended dilution: 10 microg/ml; positive tissue: placenta endothelium.

Flow Cytometry, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

4H11[APG]

1 mg/ml

IgG1

CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.

Human

2°C to 8°C

12352203