Anti-Hu CD44 Biotin

EXBIO

Anti-Hu CD44 Biotin

7

Flow cytometry: Recommended dilution: 1-3 microg/ml.

Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA

Research Use Only

MEM-85

1 mg/ml

Biotin

IgG2b

CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.

Human

2°C to 8°C

12352203