Anti-Hu CD58 Biotin
1B-232
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Porcine
Overview
- SupplierEXBIO
- Product NameAnti-Hu CD58 Biotin
- Delivery Days Customer7
- Application Supplier NoteFlow cytometry: Recommended dilution: 2-12 microg/ml.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- Clone IDMEM-63
- Concentration1 mg/ml
- ConjugateBiotin
- IsotypeIgG1
- Scientific DescriptionCD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
- ReactivityHuman, Porcine
- Storage Instruction2°C to 8°C
- UNSPSC12352203