Anti-Hu CD59 Biotin

EXBIO

Anti-Hu CD59 Biotin

7

Flow cytometry: Recommended dilution: 1-2 microg/ml.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

MEM-43

1 mg/ml

Biotin

IgG2a

CD59 (protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation.

Human

2°C to 8°C

12352203