Anti-Hu CD85j Purified Low Endotoxin

EXBIO

Anti-Hu CD85j Purified Low Endotoxin

7

Functional application: Blocking of HLA-G induced TGF-beta1 production. Flow cytometry: Recommended dilution: 1-4 microg/ml

Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot

Research Use Only

GHI/75

1 mg/ml

IgG2b

CD85j, also known as ILT-2 (Ig-like transcript 2), LIR-1 (leukocyte Ig-like receptor 1), or LILRB1 (leukocyte Ig-like receptor B1), is a member of Ig superfamily transmembrane glycoproteins named CD85. The CD85j protein is expressed on several types of immune cells (plasma cells, B cells, monocytes, T and NK cell subsets) where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.

Human

2°C to 8°C

12352203