Anti-Hu CD98 Purified

EXBIO

Anti-Hu CD98 Purified

7

Flow cytometry: Recommended dilution: 4 microg/ml. Immunohistochemistry (paraffin sections): Recommended dilution: 10 microg/ml; positive tissue: liver.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

MEM-108

1 mg/ml

IgG1

CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.

Human

2°C to 8°C

12352203