Anti-NTAL Purified

EXBIO

Anti-NTAL Purified

7

Immunohistochemistry (paraffin sections): Recommended dilution: 5 microg/ml; positive tissue: tonsil, germinal center. Western blotting: Recommended dilution: 1-2 microg/ml, incubation 60 min; positive control: RAMOS human lymphoma cell line; non-reducing conditions, 12% separating SDS-PAGE gel.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

NAP-03

1 mg/ml

IgG2a

NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.

Human, Mouse

2°C to 8°C

12352203