Anti-NTAL Purified

EXBIO

Anti-NTAL Purified

7

Western blotting: Recommended dilution: 1-2 microg/ml. Flow cytometry: Intracellular staining; recommended dilution: 1-4 microg/ml; positive tissue: RAJI human lymphoma cell line, RAMOS human lymphoma cell line.

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

NAP-07

1 mg/ml

IgG1

NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.

Human, Mouse

2°C to 8°C

12352203