Anti-SOCS3 Purified

EXBIO

Anti-SOCS3 Purified

7

Western blotting: Positive control: HeLa human cervix carcinoma cell line, reducing conditions.

Western Blot

Research Use Only

SO1

1 mg/ml

IgG2b

SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.

Human

2°C to 8°C

12352203