Mouse p53BP1 Ready-To-Use IHC Kit
IHC0642M
CategoryIHC
Product group Diagnostic
Overview
- SupplierBioss
- Product NameMouse p53BP1 Ready-To-Use IHC Kit
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Scientific Description53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
- UNSPSC41116112