Mouse PARP Ready-To-Use IHC Kit
IHC0319M
CategoryIHC
Product group Diagnostic
Overview
- SupplierBioss
- Product NameMouse PARP Ready-To-Use IHC Kit
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- Scientific DescriptionPoly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
- UNSPSC41116112