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Mouse PDGF-BB Protein (Recombinant 6His, C-terminus)

LS-G137876
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Mouse PDGF-BB Protein (Recombinant 6His, C-terminus)
  • Delivery Days Customer
    23
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Gene ID5155
  • Target name
    PDGFB
  • Target description
    platelet derived growth factor subunit B
  • Target synonyms
    IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis, platelet-derived growth factor subunit B, PDGF subunit B, PDGF, B chain, becaplermin, epididymis secretory sperm binding protein, platelet-derived growth factor 2, platelet-derived growth factor B chain, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), platelet-derived growth factor, beta polypeptide (oncogene SIS), proto-oncogene c-Sis
  • Scientific Description
    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor,it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. PDGFB also plays an important role in wound healing.
  • Storage Instruction
    -20°C,2°C to 8°C,RT
  • UNSPSC
    41116100
  • Species
    Human, Mouse