Mouse PSMP Protein (PSM-MM201)
PSM-MM201
Protein IDB1AWI6
Product group Proteins / Signaling Molecules
Overview
- SupplierKACTUS
- Product NameMouse PSMP Protein (PSM-MM201)
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity>95%
- Protein IDB1AWI6
- Protein NameProstate-associated microseminoprotein
- Scientific DescriptionPC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.
- Storage Instruction-20°C or -80°C,-80°C
- UNSPSC12352202