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SDS- PAGE analysis of recombinant mouse IL-15
SDS- PAGE analysis of recombinant mouse IL-15
SDS- PAGE analysis of recombinant mouse IL-15

Mouse recombinant IL-15 (Interleukin-15) protein, AF

PROTP48346-4
Boster Bio
ApplicationsOther Application
Product group Proteins / Signaling Molecules
Protein IDP48346
5 ug
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Overview

  • Supplier
    Boster Bio
  • Product Name
    Mouse recombinant IL-15 (Interleukin-15) protein, AF
  • Delivery Days Customer
    9
  • Applications
    Other Application
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Protein IDP48346
  • Protein Name
    Interleukin-15
  • Scientific Description
    Interleukin-15 (IL-15) is a 14-15 kDa glycoprotein with immune regulatory functions in many diverse cell types. IL-15 can be constitutively expressed in a variety of cell types stored as intracellular protein in the cytoplasm as well as transport to the cell surface, while only secreted from some cell types including monocytes, dendritic cells, epithelial cells, bone marrow stromal cells, and fibroblasts. As a pleiotropic cytokine, IL-15 mediates the crosstalk between innate immunity and adaptive immunity whose principal role is to kill virally infected cells. IL-15 plays a crucial role in the development, differentiation, and survival of NK cells. In monocytes, IL-15 induces the production of IL-8 and monocyte chemotactic protein 1 (MCP-1), which recruits neutrophils and monocytes to sites of infection. IL-15 can also act as a chemo-attractant in T lymphocytes and regulate the differentiation of T lymphocytes.
  • Source
    E.coli
  • Storage Instruction
    -20°C,-20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352202

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Protein structure of IL-15 (mouse):IL-15Ra (Sushi) (mouse):Fc (LALA-PG)-KIH (human) (rec.) (Prod. No. AG-40B-0257).IL-15 (mouse):IL-15Ra (Sushi) (mouse):Fc (LALA-PG)-KIH (human) (rec.) (#AG-40B-0257) increases proliferation of CTLL-2 mouse cytotoxic T cells.Method: Activity of IL-15 (mouse):IL-15Ra (Sushi) (mouse):Fc (LALA-PG)-KIH (human) (rec.) is measured using proliferation of CTLL-2 cells. CTLL-2 are grown in RPMI medium, glutamine, 10% FBS, 100 IU IL-2 (#AG-40B-0224) and different concentrations of IL-15 (mouse):IL-15Ra (Sushi) (mouse):Fc (LALA-PG)-KIH (human) (rec.) (#AG-40B-0257) or the control protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) (#AG-35B-0018). Cell proliferation is quantified using PMS/MTS (CellTiter 96® AQueous One Solution Cell Proliferation Assay, Promega).
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