ARG81676 Mouse sTNFR2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
ARG81676 Mouse sTNFR2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
Mouse sTNFR2 ELISA Kit
ARG81676
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameMouse sTNFR2 ELISA Kit
- Delivery Days Customer23
- ApplicationsELISA
- Assay PrecisionIntra-Assay CV: 6.9%; Inter-Assay CV: 7.7%
- Assay Sensitivity7.8 pg/ml
- Assay SpecificityThere is no detectable cross-reactivity with other relevant proteins.
- Assay Time~ 5 hours
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C
- UNSPSC41116133