Cell proliferation effect of GTX04319-pro Mouse TGF beta 1 protein, His tag (active) 48h observed by inverted microscope. (A) A549 cells cultured in DMEM, stimulated with 12.5microg/mL TGF-beta1 (B) Unstimulated A549 cells cultured in DMEM
Mouse TGF beta 1 protein, His tag (active)
GTX04319-PRO
ApplicationsFunctional Assay, Western Blot, Neutralisation/Blocking
Product group Proteins / Signaling Molecules
Protein IDP04202
Overview
- SupplierGeneTex
- Product NameMouse TGF beta 1 protein, His tag (active)
- Delivery Days Customer9
- ApplicationsFunctional Assay, Western Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ConjugateUnconjugated
- Protein IDP04202
- Protein NameTransforming growth factor beta-1
- Scientific DescriptionThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016]
- Storage Instruction-20°C
- UNSPSC12352202