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Mouse VCAM1 / CD106 Protein (Recombinant)

LS-G136248
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Mouse VCAM1 / CD106 Protein (Recombinant)
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    VCAM is a 110 kDa, cell surface integral membrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. The primary function of VCAM-1 is the mediation of leukocyte endothelial cell adhesion and signal transduction. VCAM-1 may play a vital role in the development of several diseases, including atherosclerosis and rheumatoid arthritis. The human VCAM-1 gene codes for a 715 amino acid transmembrane glycoprotein containing a 19 amino acid cytoplasmic domain, a 22 amino acid transmembrane domain, and a 674 amino acid extracellular domain. Recombinant Murine VCAM-1 is a 74.4 kDa glycoprotein comprising the extracellular domain (674 amino acid residues) of VCAM-1. Monomeric glycosylated VCAM-1 migrates at an apparent molecular weight of approximately 87-97 kDa by SDS-PAGE analysis under reducing conditions.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C,RT
  • UNSPSC
    12352202