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Mouse WISP1 Protein (WIP-MM101)

WIP-MM101
KACTUS
Protein IDO54775
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Mouse WISP1 Protein (WIP-MM101)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Formulation
    Lyophilized
  • Protein IDO54775
  • Protein Name
    WNT1-inducible-signaling pathway protein 1
  • Scientific Description
    The interplay between glioma stem cells (GSCs) and the tumor microenvironment plays crucial roles in promoting malignant growth of glioblastoma (GBM), the most lethal brain tumor. WISP1 is preferentially expressed and secreted by GSCs. Silencing WISP1 markedly disrupts GSC maintenance, reduces tumor-supportive TAMs (M2), and potently inhibits GBM growth. WISP1 signals through Integrin alpha6beta1-Akt to maintain GSCs by an autocrine mechanism and M2 TAMs through a paracrine manner.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202