Mouse/Rat Insulin (Ultra sensitive) ELISA Kit

Arigo Biolaboratories

Mouse/Rat Insulin (Ultra sensitive) ELISA Kit

23

ELISA

50 pg/ml (5 microl sample volume); 5 pg/ml (100 microl sample volume)

Mouse / Rat Insulin: 100%Hamster Insulin: DetectedRat C-peptide, Rat pancreatic polypeptide, Porcine glucagon, Human Insulin like growth factor-I and II: Not Detected

~ 3 hours

Research Use Only

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

2°C to 8°C

41116133