MOV10L1 Antibody

Cusabio

MOV10L1 Antibody

20

ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

MOV10L1

Mov10 like RNA helicase 1

CHAMP, DJ402G11.8, SPGF73, RNA helicase Mov10l1, MOV10-like protein 1, Mov10 RISC complex RNA helicase like 1, Mov10 like RISC complex RNA helicase 1, Mov10-like 1, Mov10l1, Moloney leukemia virus 10-like 1, homolog, cardiac helicase activated by MEF2C protein, moloney leukemia virus 10-like protein 1, putative helicase Mov10l1

Rabbit

IgG

RNA helicase Mov10l1

ATP-dependent RNA helicase required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the primary piRNA metabolic process. Specifically binds to piRNA precursors and promotes the generation of intermediate piRNA processing fragments that are subsequently loaded to Piwi proteins. Acts via its ATP-dependent RNA helicase activity: displays 5-3 RNA unwinding activity and probably mediates unwinding and funneling of single-stranded piRNA precursor transcripts to the endonuclease that catalyzes the first cleavage step of piRNA processing to generate piRNA intermediate fragments that are subsequently loaded to Piwi proteins.

Human

-20°C or -80°C

41116161