MPEP [96206-92-7]

MedChem Express

MPEP [96206-92-7]

5

96206-92-7

Research Use Only

99.33

C14H11N

193.249

MPEP is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects[1][2]. MPEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CC1=NC(C#CC2=CC=CC=C2)=CC=C1

-20°C,2°C to 8°C

12352200