mPGES-1/5-LOX-IN-1

MedChem Express

mPGES-1/5-LOX-IN-1

5

Research Use Only

C20H22N4O6S

446.48

mPGES-1/5-LOX-IN-1 (compound 3j) is a potent and orally active mPGES-1 and 5-LOX dual inhibitor with IC50 values of 0.92, 1.89 microM, respectively. mPGES-1/5-LOX-IN-1 shows anti-inflammatory impact[1].

O=C(C1=C(C)NC(NC1C2=CC=C(OC)C(OC)=C2)=O)NC3=CC=C(S(=O)(N)=O)C=C3

12352200