Mps1-IN-1 (dihydrochloride)

MedChem Express

Mps1-IN-1 (dihydrochloride) [1883548-93-3]

10

1883548-93-3

Research Use Only

C28H35Cl2N5O4S

608.58

Mps1-IN-1 dihydrochloride is a potent and ATP-competitive Mps1 kinase inhibitor with an IC 50 of 367 nM. Mps1-IN-1 dihydrochloride inhibit Mps1 mitotic kinase activity and abrogates spindle assembly checkpoint (SAC) function. Mps1-IN-1 dihydrochloride decreases the viability of both cancer and normal cells [1] .

OC1CCN(C2=CC=C(NC3=CC(NC4=CC=CC=C4S(=O)(C(C)C)=O)=C5C(NC=C5)=N3)C(OC)=C2)CC1.[H]Cl.[H]Cl

12352200