Mps1-IN-5 [2890819-31-3]

MedChem Express

Mps1-IN-5 [2890819-31-3]

10

2890819-31-3

Research Use Only

C24H25N9

439.52

Mps1-IN-5 is a potent and orally active Mps1 inhibitor with an IC50 value of 29 nM. Mps1-IN-5 induces Apoptosis and cell cycle arrests at G2/M phase. Mps1-IN-5 shows antiproliferative activity and anti-tumor activity. Mps1-IN-5 inhibits phosphorylation of Mps1 and induces DNA damage[1].

CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC4=C(C(N5N=C(C6=CC=CC=C65)N)=N3)C=CN4

12131703