MPST antibody [C2C3], C-term
GTX108274
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetMPST
Overview
- SupplierGeneTex
- Product NameMPST antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.57 mg/ml
- ConjugateUnconjugated
- Gene ID4357
- Target nameMPST
- Target descriptionmercaptopyruvate sulfurtransferase
- Target synonyms3-mercaptopyruvate sulfurtransferase; human liver rhodanese; MST; testicular tissue protein Li 200; tRNA thiouridin modification protein 1; TST2; TUM1
- HostRabbit
- IsotypeIgG
- Protein IDP25325
- Protein Name3-mercaptopyruvate sulfurtransferase
- Scientific DescriptionThis protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Hypoxia-Induced Changes in L-Cysteine Metabolism and Antioxidative Processes in Melanoma Cells.Read more
- MPST deficiency promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via AKT. Zhang J et al., 2022 Oct, Redox BiolRead more
- Sulfurtransferases and Cystathionine Beta-Synthase Expression in Different Human Leukemia Cell Lines. Jurkowska H et al., 2022 Jan 18, BiomoleculesRead more
- Effect of S-Allyl -L-Cysteine on MCF-7 Cell Line 3-Mercaptopyruvate Sulfurtransferase/Sulfane Sulfur System, Viability and Apoptosis. Bronowicka-Adamska P et al., 2020 Feb 6, Int J Mol SciRead more
- Dysregulation of cystathionine gamma-lyase promotes prostate cancer progression and metastasis. Wang YH et al., 2019 Oct 4, EMBO RepRead more
- New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H2S-donor. Jurkowska H et al., 2018 Jun, Amino AcidsRead more
- Hydrogen sulfide generation from l-cysteine in the human glioblastoma-astrocytoma U-87 MG and neuroblastoma SHSY5Y cell lines. Bronowicka-Adamska P et al., 2017, Acta Biochim PolRead more