Imofinostat

MedChem Express

MPT0E028 [1338320-94-7]

10

1338320-94-7

Research Use Only

99.40

C17H16N2O4S

344.38

MPT0E028 is an orally active and selective HDAC inhibitor with IC 50 s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively [1] . MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity [2] .

O=C(/C=C/C1=CC2=C(C=C1)N(CC2)S(=O)(C3=CC=CC=C3)=O)NO

2°C to 8°C

12352200