MPT0E028 [1338320-94-7]

TargetMol Chemicals

MPT0E028 [1338320-94-7]

72

1338320-94-7

Chemical

Research Use Only

MPT0E028

C17H16N2O4S

344.38

MPT0E028 is an orally active and selective inhibitor of HDAC [IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2, and HDAC6, respectively] and demonstrates good anticancer activity, as it decreases the viability of B-cell lymphomas by inducing apoptosis, possesses potent direct Akt-targeting ability, and reduces Akt phosphorylation in B-cell lymphoma.

3 years

ONC(=O)\C=C\c1ccc2N(CCc2c1)S(=O)(=O)c1ccccc1

-20°C

12352200