MPT0G211

MedChem Express

MPT0G211 [2151853-97-1]

10

2151853-97-1

Research Use Only

99.79

C17H15N3O2

293.32

MPT0G211 is a potent, orally active and selective HDAC6 inhibitor ( IC 50 =0.291?nM). MPT0G211 displays >1000-fold selective for HDAC6 over other HDAC isoforms. MPT0G211 can penetrate the blood-brain barrier. MPT0G211 ameliorates tau phosphorylation and cognitive deficits in an Alzheimers disease model. MPT0G211 has anti-metastatic and neuroprotective effects. Anticancer activities [1] [2] [3] .

O=C(NO)C1=CC=C(CNC2=C3N=CC=CC3=CC=C2)C=C1

-20°C,2°C to 8°C

12352200