MQA-P (TFA)

MedChem Express

MQA-P (TFA)

5

Research Use Only

97.36

C42H36F3N2O4P

720.72

MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO-, lambdaem=645 nm; and NIR channel at lambdaem>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images[1][2].

O=C([O-])C(F)(F)F.CN(C1=CC=C(C=C1)/C=C/C=C/C2=CC=[N+](C3=C2C=CC=C3)CC4=CC=C(C=C4)OP(C5=CC=CC=C5)(C6=CC=CC=C6)=O)C

2°C to 8°C

12162000