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MR-L2

HY-128358
MedChem Express
CAS Number2374703-19-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.23
Molecular Weight441.71
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MR-L2 [2374703-19-0]
  • Delivery Days Customer
    9
  • CAS Number
    2374703-19-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.23
  • Molecular Formula
    C19H16Cl3FN4O
  • Molecular Weight
    441.71
  • Scientific Description
    MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4) , activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC 50 of 1.2 microM [1] .
  • SMILES
    ClC1=C(F)C=C(C2=NN(CC(NCC3=CC(Cl)=CC(Cl)=C3)=O)C(CC)=N2)C=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200