MRGPRX2 Antibody

Cusabio

MRGPRX2 Antibody

20

ImmunoFluorescence, Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

MRGPRX2

MAS related GPR family member X2

G protein-coupled receptor MRGX2; Mas-related G protein-coupled receptor G3; MAS-related GPR, member X2; mas-related G-protein coupled receptor member X2; MGRG3; MRGX2

Rabbit

IgG

Mas-related G-protein coupled receptor member X2

Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core (PubMed:25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction. Acts as a receptor for a number of other ligands, including peptides and alkaloids, such as cortistatin-14, proadrenomedullin N-terminal peptides PAMP-12 and, at lower extent, PAMP-20, antibacterial protein LL-37, PMX-53 peptide, beta-defensins, and complanadine A.

Human

-20°C or -80°C

12352203