MRK 003 [623165-93-5]

MedChem Express

MRK 003 [623165-93-5]

5

623165-93-5

Research Use Only

C25H31F6N3O2S

551.59

MRK 003 is a potent, selective and orally active gamma-secretase inhibitor. MRK 003 reduce brain Abeta production in vivo. MRK 003 induces caspase-dependent apoptosis and inhibits tumor cell proliferation in vivo and in vitro[1][2][3].

FC(F)(F)CN(C[C@]1(N2)[C@H]3CC4=C(C=CC(/C=C/CN5CCC(C(F)(F)F)CC5)=C4)C[C@@H]1CC3)S2(=O)=O

12131703