MRP4 antibody [M4I-10]
GTX15602
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman, Mouse
TargetABCC4
Overview
- SupplierGeneTex
- Product NameMRP4 antibody [M4I-10]
- Delivery Days Customer9
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDM4I-10
- Concentration0.15 mg/ml
- ConjugateUnconjugated
- Gene ID10257
- Target nameABCC4
- Target descriptionATP binding cassette subfamily C member 4
- Target synonymsATP-binding cassette sub-family C member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); MOATB; MOAT-B; MRP/cMOAT-related ABC transporter; MRP4; multidrug resistance-associated protein 4; multi-specific organic anion transporter B
- HostRat
- IsotypeIgG2a
- Scientific DescriptionThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles. Mariscal J et al., 2020 Jun 10, J Extracell VesiclesRead more
- A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance. Tsukamoto M et al., 2019 Jan 10, CellsRead more
- Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4. Tsukamoto M et al., 2017 Jul 4, Int J Mol SciRead more
- An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins. Hazen M et al., 2014 Jan-Feb, MAbsRead more
- The expressions of ABCC4 and ABCG2 xenobiotic transporters in human keratinocytes are proliferation-related. Bebes A et al., 2012 Jan, Arch Dermatol ResRead more
- Localization of multidrug resistance-associated protein 2 in the nonpigmented ciliary epithelium of the eye. Pelis RM et al., 2009 May, J Pharmacol Exp TherRead more