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ProductsBack/MRP4 antibody [M4I-10]

MRP4 antibody [M4I-10]

Research Use Only
GTX15602
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    MRP4 antibody [M4I-10]
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    M4I-10
  • Concentration
    0.15 mg/ml
  • Host
    Rat
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance. Tsukamoto M et al., 2019 Jan 10, Cells
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  • An improved and robust DNA immunization method to develop antibodies against extracellular loops of multi-transmembrane proteins. Hazen M et al., 2014 Jan-Feb, MAbs
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  • Comprehensive palmitoyl-proteomic analysis identifies distinct protein signatures for large and small cancer-derived extracellular vesicles. Mariscal J et al., 2020 Jun 10, J Extracell Vesicles
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  • Localization of multidrug resistance-associated protein 2 in the nonpigmented ciliary epithelium of the eye. Pelis RM et al., 2009 May, J Pharmacol Exp Ther
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  • Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4. Tsukamoto M et al., 2017 Jul 4, Int J Mol Sci
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  • The expressions of ABCC4 and ABCG2 xenobiotic transporters in human keratinocytes are proliferation-related. Bebes A et al., 2012 Jan, Arch Dermatol Res
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