MRP6 antibody [M6II-31]

GeneTex

MRP6 antibody [M6II-31]

9

This antibody detects with MRP 6. This antibody does not cross-react with MDR 1,MRP 1, MRP 2 or MRP 3, MRP 4 & MRP 5.

Western blotting: use at a dilution of 1/20 to 1/50. FACS: assay dependent. Immunocytochemistry: use at a dilution of 1/20 - 1/50 on acetone fixed cell preparations. Immunohistochemistry: use at a dilution of 1/20 - 1/50 on frozen and formaldehyde-fixed paraffin-embedded tissuesections. Optimal dilutions / concentrations should be determined by the end user. For optimal staining in IHC, the sections should be pretreated with an antigen unmaskingsolution, for example a sodium citrate based buffer. The primary antibodyshould be incubated for about 60 minutes at room temperature when performing IHC.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

M6II-31

Unconjugated

ABCC6

ATP binding cassette subfamily C member 6

ABC34; anthracycline resistance-associated protein; ARA; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; EST349056; GACI2; MLP1; MOATE; MOAT-E; MRP6; multidrug resistance-associated protein 6; multi-specific organic anion transporter E; PXE; PXE1; URG7; URG7 protein

Rat

IgG2a

Multidrug resistance-associated protein 6

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C

12352203