MRS1334

MedChem Express

MRS1334 [192053-05-7]

10

192053-05-7

Research Use Only

99.0

C31H26N2O6

522.55

MRS1334 is a potent and selective human adenosine A 3 receptor antagonist with K i s of 2.69 nM, >100 nM, >100 nM for hA 3 , rA 1 , rA 2A , respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment [1] [2] . MRS1334 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(C1=C(C)NC(C2=CC=CC=C2)=C(C(OCC3=CC=C([N+]([O-])=O)C=C3)=O)C1C#CC4=CC=CC=C4)OCC

-20°C

12352200