MRT00033659 [1401731-54-1]

MedChem Express

MRT00033659 [1401731-54-1]

9

1401731-54-1

Research Use Only

99.77

C15H14N4O

266.30

MRT00033659 is a potent broad-spectrum kinase inhibitor of CK1 (IC50=0.9 microM for CK1delta) and CHK1 (IC50=0.23 microM). MRT00033659, a pyrazolo-pyridine analogue, induces p53 pathway activation and E2F-1 destabilisation[1].

CC1=NNC2=NC=C(C=C21)C3=CC=CC(NC(C)=O)=C3

-20°C,2°C to 8°C

12352200