Bio-Connect

MRT68921 [1190379-70-4]

HY-100006
MedChem Express
CAS Number1190379-70-4
Product group Chemicals
Estimated Purity99.71
Molecular Weight434.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MRT68921 [1190379-70-4]
  • Delivery Days Customer
    10
  • CAS Number
    1190379-70-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.71
  • Molecular Formula
    C25H34N6O
  • Molecular Weight
    434.58
  • Scientific Description
    MRT68921 is a potent NUAK1/ULK1 dual inhibitor. MRT68921 inhibits ULK1 and /b>ULK2 with IC50 values of 2.9 nM and 1.1 nM, respectively. MRT68921 can block cells autophagy and kill tumor cells by breaking the balance of oxidative stress signals. MRT68921 can inhibit cell proliferation and induce ROS production and apoptosis. MRT68921 can be used for the research of cancer, such as breast cancer[1][2].
  • SMILES
    O=C(C1CCC1)NCCCNC2=NC(NC3=CC4=C(CN(C)CC4)C=C3)=NC=C2C5CC5
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200