MRT68921 (dihydrochloride) [2080306-21-2]
HY-100006A
CAS Number2080306-21-2
Product group Chemicals
Estimated Purity99.67
Molecular Weight507.50
Overview
- SupplierMedChem Express
- Product NameMRT68921 (dihydrochloride) [2080306-21-2]
- Delivery Days Customer10
- CAS Number2080306-21-2
- CertificationResearch Use Only
- Estimated Purity99.67
- Molecular FormulaC25H36Cl2N6O
- Molecular Weight507.50
- Scientific DescriptionMRT68921 dihydrochloride is a potent NUAK1/ULK1 dual inhibitor. MRT68921 dihydrochloride inhibits ULK1 and /b>ULK2 with IC50 values of 2.9 nM and 1.1 nM, respectively. MRT68921 dihydrochloride can block cells autophagy and kill tumor cells by breaking the balance of oxidative stress signals. MRT68921 dihydrochloride can inhibit cell proliferation and induce ROS production and apoptosis. MRT68921 dihydrochloride can be used for the research of cancer, such as breast cancer[1][2].
- SMILES[H]Cl.O=C(C1CCC1)NCCCNC2=NC(NC3=CC4=C(CN(C)CC4)C=C3)=NC=C2C5CC5.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
MSDS
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