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ProductsBack/MRT68921 (hydrochloride) [2070014-87-6]

MRT68921 (hydrochloride) [2070014-87-6]

HY-100006B
MedChem Express
CAS Number2070014-87-6
Product group Chemicals
Molecular Weight471.04
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MRT68921 (hydrochloride) [2070014-87-6]
  • Delivery Days Customer
    14
  • CAS Number
    2070014-87-6
  • Certification
    Research Use Only
  • Molecular Formula
    C25H35ClN6O
  • Molecular Weight
    471.04
  • Scientific Description
    MRT68921 hydrochloride is a potent NUAK1/ULK1 dual inhibitor. MRT68921 hydrochloride inhibits ULK1 and /b>ULK2 with IC50 values of 2.9 nM and 1.1 nM, respectively. MRT68921 hydrochloride can block cells autophagy and kill tumor cells by breaking the balance of oxidative stress signals. MRT68921 hydrochloride can inhibit cell proliferation and induce ROS production and apoptosis. MRT68921 hydrochloride can be used for the research of cancer, such as breast cancer[1][2].
  • SMILES
    O=C(C1CCC1)NCCCNC2=NC(NC3=CC4=C(CN(C)CC4)C=C3)=NC=C2C5CC5.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

MSDS

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