Bio-Connect

MRTX1133(MRTX-1133)

ORB1089786
Biorbyt
CAS Number2621928-55-8
Product group Chemicals
Molecular Weight600.63
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Overview

  • Supplier
    Biorbyt
  • Product Name
    MRTX1133(MRTX-1133) [2621928-55-8]
  • Delivery Days Customer
    10
  • CAS Number
    2621928-55-8
  • Certification
    Research Use Only
  • Molecular Formula
    C33H31F3N6O2
  • Molecular Weight
    600.63
  • Scientific Description
    MRTX 1133 is a potent and selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12D protein in both active and inactive states. In preclinical studies, MRTX1133 exhibited a long half-life, an ability to bind the KRAS G12D protein in both active and inactive states, and selective inhibition of KRAS G12D mutant cancer cells.
  • SMILES
    OC1=CC(C2=C(F)C3=NC(OC[C@@]45CCCN4C[C@H](F)C5)=NC(N6CC(N7)CCC7C6)=C3C=N2)=C8C(C#C)=C(F)C=CC8=C1
  • UNSPSC
    12352200