MRTX1133(MRTX-1133)
ORB1089786
CAS Number2621928-55-8
Product group Chemicals
Molecular Weight600.63
Overview
- SupplierBiorbyt
- Product NameMRTX1133(MRTX-1133) [2621928-55-8]
- Delivery Days Customer10
- CAS Number2621928-55-8
- CertificationResearch Use Only
- Molecular FormulaC33H31F3N6O2
- Molecular Weight600.63
- Scientific DescriptionMRTX 1133 is a potent and selective KRAS G12D inhibitor. MRTX1133 targets the KRAS G12D protein in both active and inactive states. In preclinical studies, MRTX1133 exhibited a long half-life, an ability to bind the KRAS G12D protein in both active and inactive states, and selective inhibition of KRAS G12D mutant cancer cells.
- SMILESOC1=CC(C2=C(F)C3=NC(OC[C@@]45CCCN4C[C@H](F)C5)=NC(N6CC(N7)CCC7C6)=C3C=N2)=C8C(C#C)=C(F)C=CC8=C1
- UNSPSC12352200